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Boronic acid Mannich reaction (Petasis reaction) - …

Since this initial report, additional studies have shown that the Petasis reaction is quite general: a variety of amines and carbonyl compounds react with allylic, alkenyl, aryl, and alkynyl boronic acids, boronate esters, or trifluoroborates to yield products of addition of the organoboron species across an iminium ion generated in situ (Eq. 1 ...

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